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Excluded from the study were subjects taking any oral or topical prescription drug for acne vulgaris, subjects cur- rently undergoing treatment for acne vulgaris besides daily hygienic skin care, known renal or hepatic impair- ment, scheduled elective surgery or other procedures requiring general anaesthesia during the study, participa- tion in another research study involving an investiga- tional product in the past month, hypersensitivity or known allergy to any ingredients in the study agent, cur- rent use of any dietary supplement for skin health (be- sides a multivitamin), history or presence of gastric ulcer or duodenal ulcer, history of any gynaecologic condition, history of any psychiatric disorder and current smoking or smoking within the past month

: Role of L-carnitine in female infertility Ashok Agarwal et al

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Metabolism and disposition of intravenously administered acetyl-L-carnitine in healthy volunteers

The highest plasma concentrations of NAC were detected up to 1 h following oral administration with the terminal t 1/2 of about 6 h [22, 23]

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