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These peptides are used to treat opioid use disorder, wound healing, insomnia, and ulcerative colitis

PMID 23045722

These include modulation of sleep-related EEG patterns, alterations in stress hormone signaling, and changes in pain threshold responses in animal studies [7]

Many patients find that initial intensive protocols create lasting improvements in both sleep quality and stress resilience that reduce or eliminate the need for ongoing therapy, while others benefit from maintenance protocols during particularly demanding life phases

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The peptide activates the VEGFR2-Akt-eNOS pathway and increases nitric oxide production, both of which stimulate blood vessel growth