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In hypoxic conditions, endothelial FGFR deficiency in mice or FGFR inhibition in human PAECs amplifies TGF- signaling, resulting in increased EndMT and exacerbated vascular remodeling

Understanding potential interactions and synergies helps inform these decisions

2022;21(1):69 Rico-Blazquez M

The central nervous system, particularly the brain, is highly susceptible to oxidative stressan imbalance between free radicals and antioxidants that can lead to cellular damage