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doi:10.2174/1381612826666200523180301 National Center for Biotechnology Information

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As a severe X-linked neurodevelopmental disorder, RTT predominantly affects females, with the majority of cases resulting from MECP2 mutations both within and outside the methyl-CpG binding domain (MBD) (98)

Berberine can be found in various medicinal plants, common types are Berberis vulgaris , Coptis chinensis , and Hydrastis canadensis

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