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The central activation on the hypothalamus contributes to robust regulation of appetite and satiety, while peripheral effects on the gastrointestinal system lead to improved glycemic outcomes

Dyes were added 30 minutes prior to the end of treatment, followed by immediate sample collection

ERK1/2 activation upregulates collagen gene expression and promotes cell proliferation critical for fibroblast proliferation, while p38 MAPK inhibition reduces inflammatory response

The seminal vesicles, prostate gland, and bulbourethral glands contribute to the production of semen

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Gardner MP, Lightman S, Sayer AA et al (2013) Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages: an individual participant meta-analysis