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Currently, four monoclonal antibodies are in clinical trials for the treatment of CD38 + malignancies [41-49]

The remaining changes to the Shared Savings Program regulations are not estimated to have an impact on program spending at the aggregate level

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A 14-year-old boy presented with frontal headache, fatigue, persistent low-grade fever, growth failure, and weight gain before being diagnosed with a large suprasellar mass invading the third ventricle, causing obstructive hydrocephalus with dilatation of the lateral ventricles