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Nanotechnology allows for renal-specific drug targeting in CKD management, potentially reducing dosage levels and frequency with fewer side effects [230]

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10.1111/j.1365-2605.2008.00951.x 244

Experimental elevation of Brk conferred resistance of breast cancer cells to cetuximab (an EGFR-blocking antibody)-induced inhibition of cell signaling and proliferation, whereas knockdown of Brk sensitized the cells to cetuximab by inducing apoptosis