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However, excessive levels of ROS can overwhelm the skins antioxidant defenses and potentially contribute to the development of inflammatory skin disorders (24)

Interv Med Appl Sci

Drop back to the last tolerated dose and stay there for 6-8 weeks before attempting escalation again

Another study used this conjugate to create a bifunctional tool with mertansine, also called DM1a tubulin inhibitor used to create an antibodydrug conjugate [118]