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L.CaminosJ

Peptide drugs that target local inflammation and angiogenesis demonstrate reduced lesion size in animal models and early human safety data

PubMed DOI Dalmasso G, Charrier-Hisamuddin L, Nguyen HTT, et al

Furthermore, Cart CaSR / mice with cartilage-specific ablation of CaSR gene develop shorter, undermineralized skeletons due to delayed differentiation of hypertrophic chondrocyte (44)

Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis

IPF usually develops in the sixth to eighth decades of life and has a high mortality rate, with approximately 50% of IPF patients dying within 23 years, which is worse than many malignancies 1,2