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Circulation 119 , 30933100 (2009)

A primary and critical distinction must be drawn between direct and indirect release pathways. Direct application (in situ remediation): this pathway involves the intentional, large-scale introduction of ENMs directly into a contaminated environment

Exosomes mediated fibrogenesis in dilated cardiomyopathy through a MicroRNA pathway

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For example, in AD they may promote A clearance and IL-10/Arg1 expression, while in PD they may inhibit NF-B and reduce dopaminergic neuron death, and in ALS they could dampen mutantproteininduced microglial activation

(2008) 23:CD004611