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8+ Weeks: Long-Term Remodeling Few published BPC-157 studies extend beyond 8 weeks, but the available data and general tissue biology suggest: Tendon and ligament remodeling continues for 36 months post-injury regardless of intervention BPC-157's primary contribution (angiogenesis, growth factor upregulation) is most impactful in the first 48 weeks Continued dosing beyond 8 weeks is not well-studied

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Fibroblast Growth Factor (FGF) (3,500 mg) Aids skin repair, enhances collagen, and helps reduce signs of aging

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doi: 10.1016/j.ibneur.2025.01.004 83 de BoerLMWiegmanAKroonJTsimikasSYeangCPeletierMCet al

Moreover, the accumulation of somatic mtDNA mutations a recognized feature of biological agingappears to be accelerated in PLWH