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The pathogenesis of IBD is multifactorial, with core pathological mechanisms involving intestinal barrier dysfunction, immune dysregulation, microbial dysbiosis, and oxidative stress

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However, hypoxia resulting from tumor vascular degeneration during anti-angiogenic therapy may increase the expression of various pro-angiogenic factors

Archbishop Romero lived for a simple yet profound purpose

Similarly, the decline of aspartate aminotransferase (AST) and alanine aminotransferase (ALAT) indicates that drought stress inhibits the amino-acid metabolism and synthesis of other metabolites

Cancer Treat Rev 1985