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Perspectives and challenges Abnormal activation of Wnt/-catenin signalling promotes the progression of various diseases and oncogenic transformation of tumours, making key factors involved in Wnt/-catenin signal transduction attractive therapeutic targets

These properties give imidipide certain advantages in drug preparation and biological applications

Most importantly, the dimeric macrocycles achieved the same maximal phosphorylation as hHGF, indicating that they can act as fully functional agonists of Met

DCP-1, a Drosophila cell death protease essential for development

doi: 10.1007/s00109-023-02407-3 77 FujitaK.YamauchiM.ShibayamaK.AndoM.HondaM.NagataY

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