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Figure 1 2.1 Dysregulated iron metabolism drives ferroptosis in periodontitis Iron is an essential trace element for cellular physiological activities, and its homeostasis is tightly regulated by a complex network encompassing iron uptake, storage, release, and efflux

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After pooling the fractions containing pure 3,4- cis -leucocyanidin ( 6 ), MOPSO was added to a final concentration of 10 mM, the pH was set to 6.2 using 5 N NaOH and the pooled fractions were rotary-evaporated to a concentration of 7 mM of 3,4- cis -leucocyanidin ( 6 ), quantified by HPLC-UV (280 nm) with an external calibration curve with 3,4- trans -leucocyanidin ( 14 )

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Visualizing vasculature and its response to therapy in the tumor microenvironment

Sci Adv (2019) 5(3):eaav2104