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The authors report, for the first time to their knowledge, the increased expression of specific genes and proteins related to cell death receptors

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Moreover, concerns about cell viability, immune rejection, tumourigenicity, and long-term safety limit widespread adoption [97]

Cell 171, 11511164.e16

Conclusion As a short-term effect of the PGA-collagen tube for peripheral nerve injuries, the PGA-collagen tube facilitated the recovery from nerve degeneration at the heat stimulation-induced sensory threshold, motor evoked potentials, and upon pathological observation of the myelinated nerve fiber