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NADPH oxidase (NOX) is an important source of ROS in the cochlea, and NOX activity increases the expression of genes involved in the excitatory pathway, damages the cochlea, and ultimately causes ARHL [92]

For each study, data were abstracted for: Author, year of publication, country, type of study, model of cancer or patients, type of honey or composition, dose and duration, comparator, and key findings

63 The delivery of senolytics in AD mice reduces the A load and the levels of proinflammatory factors, thereby enhancing cognitive funciton

119 In contrast, tumor-specific neoantigens arise from somatic mutations, gene fusions, or aberrant splicing events 120,121 and are absent from normal tissues, making them highly immunogenic

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