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Studies using hippocampal preparations revealed that EPSCs persisting in VGLUT1-KO neurons, apparently mediated by VGLUT2, exhibited higher release probability and rapid recovery after synaptic depression (Fremeau et al., 2+ -dependent process

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Szymusiak M, Hu X, Plata PAL, Ciupinski P, Wang ZJ, Liu YJ (2016) Bioavailability of curcumin and curcumin glucuronide in the central nervous system of mice after oral delivery of nano-curcumin

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This includes: Gradual weight loss of 710% of body weight in overweight or obese individuals, which has been shown to reduce liver fat and inflammation Regular physical activity of at least 150 minutes of moderate-intensity exercise per week Dietary changes including reducing refined carbohydrates, saturated fats, and sugar-sweetened beverages whilst increasing consumption of vegetables, whole grains, and lean proteins

10.3390/molecules28031178 47