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8 Indeed, the cumulative cardiovascular event rates in hypertensive patients with high-grade endothelial dysfunction were higher than in hypertensive patients with low-grade endothelial dysfunction

Secondary structure was composed of 84 strands, 199 helixes, and 276 coils (Fig

Moreover, Study conducted on mouse model reported that LPS can downregulate occluding (a protein in tight junction) in the intestinal epithelial cells and upregulate TNF-, which promotes the expression of -synuclein ( Several research studies suggested that altered GM plays a crucial role in accelerating oxidative stress, inflammation and DNA damage

10.1038/s41392-024-01743-1 [DOI] [PMC free article] [PubMed] [Google Scholar] Lourida I., Soni M., Thompson-Coon J., Purandare N., Lang I

The existing body of evidence is largely limited to small-animal studies, characterized by heterogeneous delivery methods and a lack of standardized dosing or long-term safety data