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Pernicious anemia is an autoimmune disease that makes it hard for the small intestine to soak up B12

Park J, Overbey EG, Narayanan SA, Kim J, Tierney BT, Damle N, et al

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Preclinical studies have shown that GNK-301 can be used to detect the presence of the HERV-K ENV protein in a laboratory test and that it can then be used as a medicine to neutralize the harmful effects of HERV-K ENV, protecting neurons and preventing damage to the blood-brain barrier

In a clinical trial of semaglutide injection for weight loss (Wegovy) in patients with T2DM and a BMI of 27 kg/m2 or more, hypoglycemia (defined as a plasma glucose less than 54 mg/dL) was reported in 6.2% of semaglutide-treated patients versus 2.5% of placebo-treated patients