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Therefore, improving the inflammatory response and oxidative stress in patients with ARDS through metabolic regulation, such as improving mitochondrial function, regulating lipid metabolism, and enhancing the ability of the antioxidant system, may become an important direction for future ARDS treatment strategies

Nature 453 , 767769 (2008)

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Cholesterol is necessary for the formation of the plasma membrane microdomains known as lipid rafts, which organize the signalling molecules involved in cancer development and progression