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Future studies might investigate the effects of CIT and CIT+GSH in individuals with prediabetes

Lactobacillus and Bifidobacterium residing in the gastrointestinal tract possess the capacity to enzymatically convert nitrate and nitrites into nitric oxide (NO), thereby endowing the gut epithelia with a substantial reservoir of NO (Das and Ganesh, 2023)

Available at: 34 InoueKGuoRLeeMLEbrahimiRNeverovaNVCurrierJWet al

Western blot analysis The levels of cellular proteins were quantified using Western blot analysis by utilizing primary antibodies: anti--catenin (1:1000), anti-pGSK3 (Ser9, 1:1000), anti- tGSK3 (1:1000), anti-cyclin D1 (1:1000), anti-p-Akt (1:1000), anti-tAkt (1:1000) (all from Cell Signaling Technology, Danvers, MA, USA), or anti-GAPDH (1:5000

AIC and BIC values are representative of the distance between the fitted likelihood of the model and the unknown true likelihood function of the data, with the BIC criterion penalising model complexity more heavily than the AIC 20,24

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