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Nature 524 (7565), 309314

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Avoid inhalation, ingestion, and contact with skin or eyes

Melatonin could resolve hyper-inflammatory conditions in COVID-19 and PASC by down-regulating proinflammatory cytokines (i.e., TNF-, IL-1, IL-6, and IL-8) and increasing anti-inflammatory cytokines such as IL-10 660,661

doi: 10.1038/nm.4050 307 VeenGGiltayEJDeRijkRHvan VlietIMvan PeltJZitmanFG

doi: 10.1038/s41467-018-05470-4 80 SadlierCAlbrichWCNeogiULunjaniNHorganMOToolePWet al

(2 R ,4 R )-2-(2-Oxoacetyl)thiazolidine-4-carboxylic acid 37b : The title compound was observed when cysteine (43.4 mM) was exposed to HCHO (10 equiv.) after 1 h