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Dihexa acts as an analog of angiotensin IV, a compound known to stimulate brain-derived neurotrophic factor (BDNF)

Increased expression of the immediate response gene, early growth response gene-1 (egr-1), was shown in Caco-2 cells in vitro (Tkalcevic et al., 2007)

Evidence for P13 kinase and PKC involvement

Early studies suggest that it may support memory and learning by repairing neural pathways and promoting the connections among brain cells

The degree of activation and fatigue plays a crucial role in defining the body's immune responses against tumors and the effectiveness of immunotherapy

Gain in MET copy number is present in almost 16% of the HNSCC patients and associated with an increased c-MET expression and poorer outcome [87]