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SKU: 67234154908
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Description

Hikosaka et al., 2022

High proline content, acid-stable

Aging is associated with reduced mitophagy and lysosomal degradation, along with increased ER folding stress, which affects signaling at membrane contact sites, resulting in sustained proteostasis imbalance

Aging 27 , 318323 (2006)

In the context of cerebral ischemia, astrocytes are especially important in regulation and maintenance of glutamate during acute injury, which causes excitotoxicity and perturbates calcium influx resulting in cell death (Brancaccio et al., 2017)