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[DOI] [PubMed] [Google Scholar] 48.Kemmel V, Klein C, Dembele D, et al

Wide variety of bioactive compounds like resveratrol, curcumin, naphthazarin, genistein, and carnosic acid and berberin have been reported as Nrf2 activators that show positive effects in neurodegenerative disorders by protecting dorsal root ganglion (DRG) neurons from glucose-induced injury also by antioxidant activity in primary spinal cord astrocytes exposed to H 2 O 2 [59]

NNMT in Metabolic Regulation Kraus et al

These nanozymes can scavenge reactive oxygen species (ROS), modulate inflammatory pathways, and reverse mitochondrial dysfunction, providing notable neuroprotection and pain relief for affected individuals

The signaling pathways through which ferroptosis affects depression are predominantly mediated by GPX4

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