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Given the prevalence of HHCY in HF and the deleterious effects of HHCY on cardiac function, it is surprising that this kind of study has never been considered and that data related to the effects of these vitamins in HF are lacking

Our findings highlight a critical role of GADD45 in maintaining SIRT1 stability and limiting lipogenesis, providing new insights and potential therapeutic strategies for MASLD

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Table 1 Recommended daily intake for each B complex vitamin and the associated neurological and psychiatric manifestations resulting from their deficiencies