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A key focus should be the interaction between the HIF-1-regulated iron metabolism axis (such as transferrin receptor 1 and ferritin light chain) and ferroptosis-related molecules including GPX4 and Nrf2, to establish a dynamic model connecting hypoxiaischemia, iron dysregulation, and oligodendrocyte ferroptosis, and to identify stage-specific vulnerability across oligodendrocyte maturation

In addition, we found that RSL3 not only induced ferroptosis in prostate cells, but also further promoted the increase of autophagy levels

Conclusion: GCKR P446L increased TG and glycogen accumulation suggesting a cell autonomous effect on TG and glycogen accumulation

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Karaplis, A

White flowers on 12- to-18-inch-tall upright racemes bloom in early to mid spring