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PMID: 25225435

Consistent with a moderate increase of these well-described changes in healthy aging, we observed significantly higher levels of malondialdehyde (MDA), a marker for circulating levels of lipid peroxides, in older adults compared to the levels of young subjects (means, young = 0.136, older adults = 0.158 mol/L, p -value 300 uM in older adults is within the range of what has been described as being associated with elevated cardiovascular risk compared to that of young subjects (El-Khairy et al., 2001)

Lack of adaptive detoxification enzyme induction is known to occur in response to accumulating toxins [63]

The Fas inhibitor C75 (Sigma, St Louis, MO) was dissolved in DMSO and added to differentiation media at a final concentration of 100 M for 18 h following 18 h of differentiation

Clinical evidence shows that colon dialysis combined with Chinese herbal enema can treat chronic renal failure by reducing the serum creatinine level and delaying the progression of kidney disease [193]

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