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In the vegan community it is often recommended as a source of vitamin B12 but it must be fortified with it as yeast cannot produce B12

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But its easy passage through cell membranes means it is still efficiently converted to NAD+ when taken orally, which raises blood NAD+ levels to support healthy cellular energy and healthy aging

Interestingly, the levels of this H2B modification increase in replicative aged cells (Rhie et al., 2013)