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Thus, activation of AMPK modulates the miR-206/HDAC4/cyclin D1 signaling pathway, chiefly targeting HDAC4, to suppress airway smooth muscle cell proliferation and, therefore, has potential value in the prevention and treatment of asthma by alleviating airway remodeling

10.1016/j.expneurol.2022.114103 72 LinT

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These potent anti-androgenic chemicals are finasteride, which blocks the conversion of testosterone to DHT by inhibiting 5--reductase, and the three AR antagonists: flutamide, vinclozolin and procymidone

Although 25(OH)D3 is biologically inactive, the enzyme 1-hydroxylase converts it to calcitriol (1,25(OH)2D3), which is biologically active form

Melatonin and empagliflozin can inhibit ferroptosis and protect against doxorubicin-induced cardiotoxicity