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Apoptosis Initiation: Once liberated, p53 translocates to the mitochondria and activates BAX/BAK, triggering intrinsic apoptosis (cell death) specifically in the senescent cell

while this risk is less relevant for injectable forms, caution is still advised in patients with reactive airway diseases

Growth hormone levels decrease approximately 14% per decade after age 30, a phenomenon termed somatopause

Significant progress has been made in promoting equality, diversity, and inclusion

The market for a safe and efficacious drug is potentially huge, but the value of currently approved therapies does not reflect this potential, this being evidence of their limited efficacy and side-effect profiles

doi:10.1073/pnas.0502738102