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8,9,10,11 Because of its tumor suppressor function and universal mutation in human cancer, p53 is a highly appealing target for new anticancer therapies

Cellular thermal transfer assay (CETSA) Human primary chondrocytes and C28/I2 cell lines were cultured in complete medium under typical conditions (37 C, 5% CO, humidified atmosphere) until reaching a cell density of approximately 90%

Dreishpoon MB et al (2023) FDX1 regulates cellular protein lipoylation through direct binding to LIAS

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FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b