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Description

Ferroptosis has been described as a consequence of epileptic seizures, as certain biomarkers of ferroptosis such as 4-hydroxynonenal (4-HNE), malondialdehyde (MDA), glutathione peroxidase 4 (GPX4), cyclooxygenase-2 (COX-2), and glutathione (GSH) have been found to be altered in plasma and in brains of epileptic patients and animal models of experimental epilepsy [3133]