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Through this network-oriented reevaluation, we aim to provide a unifying theoretical perspective that organizes fragmented observations, highlights key regulatory hubs, and generates testable predictions to guide future basic research and the development of potential clinical intervention strategies

doi: 10.7717/peerj.13992 5 CalcaterraVVerduciECenaHMagenesVCTodiscoCFTenutaEet al

Ultimately, elevated PSAT1 promotes serine metabolism and LUAD cell proliferation [95]

MMR protein complexes repair DNA damage, but not cisplatinDNA complexes, and unsuccessful repair initiates cell death

NADP-dependent isocitrate dehydrogenase (NADP-ICDH) from Arabidopsis roots contributes in the mechanism of defence against the nitro-oxidative stress induced by salinity

Stock solutions of amino acids were prepared in pure milliQ water whereas stock solutions of EDTA, DTPA and NTA were neutralized with 0.1 M NaOH to pH 7-8 and further diluted into reaction buffer