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3 Advances in emerging drug therapies: genetically targeted therapies TDP-43 is an RNA-binding protein, and cytoplasmic TDP-43 aggregates are present in sporadic and familial ALS, in addition to familial ALS caused by mutations in SOD1 , and its aberrant aggregation and aberrant function have been implicated in the pathogenesis of ALS (31, 32)

Are we bypassing any learned lessons by taking quick fixes

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High prevalence of Methanobrevibacter smithii and Methanosphaera stadtmanae detected in the human gut using an improved DNA detection protocol

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