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This interaction not only impairs immune-mediated tumor clearance but also contributes to the development of resistance to immunotherapies in PC [104]

Inform your doctor beforehand if you have a history of liver, heart, or kidney diseases

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For example, in hepatocellular carcinoma (HCC), ferroptosis serves as a tumor-suppressive mechanism in early stages but becomes dysregulated in advanced disease, suggesting that dynamic modulation may be necessary during different phases of neurodegeneration

E., Winkler L., Lassowski B., Mueller S

Relatively few in vitro studies, however, have investigated the mechanism of action of and/or resistance specifically associated to T-DXd