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Description

Intranasal GSH in Mischley et al

This absence of IGF-1 stimulation is critical for appetite neutrality because IGF-1 has known effects on hypothalamic neuropeptide expression, including alterations to neuropeptide Y (NPY) and agouti-related peptide (AgRP), both potent appetite stimulators

Additionally, growing evidence suggests that the therapeutic efficacy of natural products in AD may be modulated by genetic factors, particularly the apolipoprotein E (APOE) genotype (Sharifi-Rad et al., 2022)