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The SURPASS program (for type 2 diabetes) and SURMOUNT program (for obesity) together enrolled over 20,000 participants across multiple Phase III trials

Glucagon-like peptide-1 receptor: Mechanisms and advances in therapy

Dark blue circles are genes that have expression significantly correlated with Lm

doi: 10.1021/acs.joc.8b01237

The efficacy of GA is largely due to its ability to stimulate insulin secretion from cells, reduce insulin resistance, and inhibit the intestinal absorption of glucose (Figure 4)