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However, the downregulated proteins exhibited enrichment in metabolic pathways, particularly the catabolic process ( p adjusted = 0.0011), cellular catabolic process ( p adjusted = 0.0006), and cytoplasmic translation ( p adjusted = 3.2E-07) (Supplementary Figure S6C

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doi: 10.3389/fcell.2026.1760517 Received 04 December 2025 Revised 02 March 2026 Accepted 16 March 2026 Published 31 March 2026 Volume 14 - 2026 Edited by Bridget Martinez, University of Nevada, Reno, United States Reviewed by Raja Singh Paulraj, Marshall University, United States Dongling Dai, Shenzhen Childrens Hospital, China Updates Copyright 2026 Zhang, Tang, Chen, Akanyibah and Mao