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*Correspondence: Hongwei Guo, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Supplementary Tables 12 and 13 and Supplementary Tables 2024 show the top GSEA gene sets for the up- and downregulated genes in siGSTO1 and drug treatment Bru-Seq data sets

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Constructs and CRISPR/Cas9-mediated EBNA1 deletion For EBNA1 knockout cell line construction, the plasmid lentiCRISPR-v2-EBNA1 for EBNA deletion was kindly supplied by Prof