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The KRAS mutations are observed in over 35% of patients of the NSCLC subtype [63, 64], together with significant Treg infiltration, particularly the KRAS G12D mutation [65]

10.1111/jcmm.15230 44 KatoH.KanaokaM.YanoS.KobayashiM

(2019, February 15)

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Beyond its proteolytic function, PR3 serves as the major autoantigen in anti-neutrophil cytoplasmic antibody-associated vasculitis, conferring special relevance in autoimmune diseases ( CatG exhibits distinctive dual biological characteristics, effectively degrading various extracellular matrix proteins while possessing significant antimicrobial activity