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p53 inhibits the transcription of SLC7A11 by directly binding to its promoter in fibroblasts and certain cancer cells, which then affects the GPX4-regulated classical pathway and ultimately leads to ferroptosis (Fig

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Autophagy and amyotrophic lateral sclerosis: the multiple roles of lithium

In this study, Lactococcus lactis was used as a vector to deliver BPC-157 to the surface of GI

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reported that Asp and Asn in colon cancer cell lines could inhibit their activities by binding to LKB1 (encoding filament, threonine kinase, and direct phosphorylation of protein products to activate AMPK), thus inhibiting AMPK-mediated p53 activation