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Further clinical studies are required to establish the usefulness of L-carnitine supplementation in hypothyroidism (see Table 1 )

Although it remains unknown as to how the inhibition of the interaction with BRD4 occurs in the context of full-length ASXL1, the intramolecular contacts with the C-terminal region of ASXL1 that occlude ASXL1 EBM could play a role

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This is comparable to study findings from Spain (40) and Italy (72)

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