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doi: 10.1093/toxsci/kfl077 13 BorudeP.BhushanB.GunewardenaS.AkakpoJ.JaeschkeH.ApteU

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Targeting serine metabolism also plays an essential role in precision and personalized cancer therapy

Inhibition of GT in melanoma cells significantly increased the radiosensitivity of a high GT variant (Prezioso et al., 1994b)

In addition, pupae in the BT-supplemented group were significantly smaller than pupae from thiamine- and AT-supplemented medium, with an average size of 2.25 0.22 mm 2 compared to 2.48 0.21 mm 2 in the thiamine group and 2.40 0.24 mm 2 in the AT group, corresponding to reductions of approximately 9% and 6%, respectively (Figure 4D)

Interferon-inducible protein-10 (IP-10), a proinflammatory chemokine whose combination with its receptor CXCR3 activated multiple signaling pathways to recruit lymphocytes and lead to the influx of inflammatory cytokines into inflamed mucosa, could be selectively degraded by lactocepin, a protease encoded by Lactobacillus casei or Lactobacillus paracasei