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Furthermore, ROS can be released in response to a variety of stimuli, such as TNF- and lipopolysaccharide [3646, 169] and they serve as intracellular signals for the activation of redox-sensitive transcription factors [2, 3, 1618, 26, 27, 3646, 164170]

6 Leucovorin Calcium vs Alternative Sources of Folic Acid Leucovorin Calcium (folinic acid) is the primary folic acid source studied for management of ASD

Ostergaard L, Stankevicius E, Andersen MR, Eskildsen-Helmond Y, Ledet T, Mulvany MJ, Simonsen U (2007) Diminished NO release in chronic hypoxic human endothelial cells