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[375] showed in these animal models and in RAW264.7 cells that chlorogenic acid prevented colitis by downregulating miR-155 expression and inactivating the NF-B/NLRP3 inflammasome pathway in macrophages

In: National Cancer Institute

Sudo K, Xiao L, Wadhwa R, Taketa T, Blum MA, Skinner HD, Lee JH, Bhutani MS, Weston B, Komaki R, Rice DC, Swisher SG , Hofstetter WL, Ajani JA

B.RajR.YangE.et al (2022)

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a maximum number of helix stabilization residues will be utilized (e.g., leu, ala, or lys) the capping residue will be considered (for example Gly is an exemplary N-capping residue and/or C-terminal amidation can be used to provide an extra H-bond to stabilize the helix