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This is dependent on the 3-4-fold increase in total IGF-I (50), which consequently results in an increase in unbound IGF-I, even if the increase is matched with the same absolute molar increase in IGFBP-3 (and complexed with ALS in a ternary complex)

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The company states that medications are tested for potency (correct concentration of active ingredient), sterility (free of foreign organisms), pH level (to minimize irritation), and endotoxicity (adherence to safety recommendations)

Unsafe doses are much larger than those discovered in these studies

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