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Zhao, W., et al

His/His SULT1A1 + null GSTM1/GSTT1: Low SULT1A1 sulfation reduces the parallel catechol estrogen inactivation route increasing the proportion of catechol estrogens that remain available for quinone-forming oxidation

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[PubMed: 10744772] 623

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found that monocyte-derived macrophages from patients with CD were less susceptible to cell death induced by phorbol-12-myristate-13-acetate and speculated that this could result in the prolonged presence of pro-inflammatory macrophages in the gut and incomplete resolution of inflammation [9]