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with permission.) During thymidylate synthesis, 5,10-methylene-THF is oxidized to DHF (dihydrofolate)

Elsby R, Kitteringham NR, Goldring CE, Lovatt CA, Chamberlain M, Henderson CJ et al

(2024) 11:e2404073

115 In a word, disturbances in estrogen homeostasis in the breast tissue may promote breast cancer progression and metastasis

Furthermore, Met exerts an immunomodulatory effect of collagen induced arthritis by inhibiting Th17 cell differentiation and upregulating Treg differentiation [148]