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Catalase deactivates H 2 O 2 to produce water and oxygen, with Fe or Mn serving as cofactors

A broad range of nutritional interventions is possible, so a pragmatic model that rationalises their indications and use may be helpful in clinical practice (Figure 2)

Glutathione is produced in almost every cell in your body and can be found in two forms: reduced and oxidized

The induction of MPT triggers release of intermembrane proteins such as apoptosis inducing factor (AIF) and endonuclease G into the cytosol and their translocation to the nucleus, causing nuclear DNA fragmentation and activation of regulated necrosis

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Sderdahl T, Enoksson M, Lundberg M, Holmgren A, Ottersen OP, Orrenius S et al